Welcome to the Topological Molecular Biology Lab at UC Davis!

Our group is interested in applications of topological methods to understand the three dimensional organization of the genome in different organisms, to study genome rearrangements and copy number changes in cancer, and to model the action of enzymes such as recombinases and topoisomerases. We use a combination of mathematical and computational methods including tools fromÂ low-dimensional topology, computational knot theory, random knotting, algebraic topology, persistence homology, combinatorics, statistics, Monte Carlo methods and computer visualization.

We are deeply committed to promoting diversity in mathematics and the sciences. Our goal is to lead a truly interdisciplinary and vertically integrated group at the interface of mathematics and molecular biology. Find description of some of our research projects, our publications, and some of our dissemination and outreach efforts.